Combunox For acute, moderate to severe pain
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Efficacy
Patient Relief with COMBUNOX
Patient Satisfaction
Safety and Tolerability
Dosing
Patient Education Material
Long-Lasting Relief with COMBUNOX
In an abdominal/pelvic surgery model
Long duration of pain relief with COMBUNOX2
Long duration of pain relief with COMBUNOX

Rapid Relief with COMBUNOX
In a pooled dental surgery model
Fast onset of pain relief with COMBUNOX3
Fast onset of pain relief with COMBUNOX
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References:
1. COMBUNOX® (Oxycodone HCl and Ibuprofen) Tablets Prescribing Information. Forest Pharmaceuticals, Inc., St Louis, Mo.
2. Singla N, Pong A, Newman K, for the MD-10 Study Group. Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study. Clin Ther. 2005;27:45–57.
3. Newman K, Zheng H. Combination of oxycodone HCl and ibuprofen, compared to ibuprofen or oxycodone HCl alone, is more rapid and effective in alleviating postoperative pain. Presented at: 22nd Annual Scientific Meeting of the American Pain Society; March 20–23, 2003; Chicago, Ill.
4. Data on file, Forest Laboratories, Inc.
5. Litkowski LJ, Christensen SE, Adamson DN, Van Dyke T, Han S-H, Newman K. Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blind, placebo-controlled, single-dose, parallel-group study in a dental pain model. Clin Ther. 2005;27:418–429.